Ovaries of Rats with Gonadectomized Parabionts bearing Intrasplenic Ovarian Grafts.

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on Intrasplenic Ovarian Grafts *

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The formation of tumors in intrasplenic ovarian grafts in castrated hosts has been observed re peatedly in rats (1, 10) and mice (2, 7, 8, 9). In all the studies undertaken up to this time both young hosts and donors were used; in fact, autologous grafts have been made in most of the experiments. The theory has been proposed that ovarian tumorigcnesis occurs in the intrasplenic and intrapancrea...

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A Strain Male Mice Bearing Ovarian Grafts*

The early studies of Murray (11) suggested that male mice that had been castrated and trans planted with ovaries developed mammary cancer with approximately the same frequency as did virgin female mice of the same strain. Later, Loeb et al. (10), in a preliminary report in which no data were presented, stated that “aftertransplantation of ovaries into castrate male mice, the cancer rate and p...

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Cholesterol metabolism in gonadectomized rats.

In studies in which tissue concentrations of cholesterol and total lipids were determined in male and female rats fed a control diet containing fat, the effects of gonadeetomy were much smaller than in animals fed a fat-free diet in which gonadeetomy tended to reverse the sex differences observed in these lipid values. Other phases of lipid metabolism were shown to be sex-linked as well. Gonade...

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Morphology, secretion, and transplantability of ten mouse ovarian neoplasms induced by intrasplenic ovarian grafting.

Ovaries grafted into the spleens of gonadecto mized hosts are transformed into neoplasms in rats (2,14), mice (4, 7, 9, 11, 12), and rabbits (15). Al though there is a rapidly growing literature on the production of such ovarian neoplasms, very few reports have been concerned with their transplantability. Li and Gardner (11) stated that they made successful primary subpassages of several neopla...

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ژورنال

عنوان ژورنال: Proceedings of the Japan Academy

سال: 1952

ISSN: 0021-4280

DOI: 10.2183/pjab1945.28.97